Mechano Growth Factor — a splice variant of IGF-1. Studied in exercise physiology research for its role in satellite cell activation and muscle tissue repair responses to mechanical loading.
MGF is a research compound available through our china peptide catalog as a finished, lyophilized vial from an established Chinese manufacturer. It belongs to the IGF-1 splice variant Ec peptide (C-terminal fragment)
Research Areas
Skeletal muscle biology, satellite cell activation, mechanotransduction, IGF-1 isoform pharmacology, tissue repair
Available Variants
| Name | Strength | Pack Size | Purity | Availability |
|---|---|---|---|---|
| MGF | 2 mg | 10 vials | ≥98% | In Stock |
Specification Highlights
Quality & Testing
Testing method: HPLC / LC-MS ([“HPLC”,“LC-MS”,“Water Content”]) . Products are supplied against the specification shown on the applicable product page. The standard catalog purity specification is ≥98% unless otherwise stated. Product-specific specifications and quality-control information may vary by compound and batch. Available documentation: .
**Where provided, these documents reflect the manufacturer’s batch testing for this compound.
Research Areas
Satellite Cell Activation Research The primary research interest in MGF is its proposed role in activating skeletal muscle satellite cells (myosatellite cells) — quiescent stem cells that become activated following muscle damage or mechanical overload. Studies in rodent muscle injury models have examined satellite cell proliferation and myotube formation markers following MGF administration. The peptide’s local expression pattern (distinct from systemic IGF-1) and proposed non-IGF-1R mechanism make it a unique tool for studying satellite cell biology independently of canonical growth factor receptor pathways. Mechano-Transduction and Muscle Overload Models Research has examined MGF expression patterns in skeletal muscle following eccentric exercise, stretch overload, and myotoxin-induced injury in animal models. Studies tracking Ec peptide production relative to mechanical stimulus magnitude, timing, and recovery have contributed to understanding of how muscle senses and responds to mechanical challenge. MGF serves as a molecular marker of local IGF-1 Ec isoform upregulation in mechanobiology research. IGF-1 Isoform Pharmacology The IGF-1 gene produces multiple splice variants (IGF-1Ea, IGF-1Eb, IGF-1Ec in humans) with distinct tissue expression patterns and proposed functional roles. MGF (IGF-1Ec) research explores how the Ec C-terminal extension confers functional properties absent in the common Ea isoform — particularly local tissue action and satellite cell targeting. Comparative studies using Ea versus Ec peptide fragments in matched models are a key tool in IGF-1 isoform pharmacology. ## Sourcing MGF From China
MGF is available through our platform as a china peptide sourced directly from an established Chinese manufacturer. Three points define how we handle it:
- Factory-direct, not trader-sourced. We confirm availability and specification with the manufacturer before the order is confirmed. There is no intermediary resale of unknown-origin vials in this catalog.
- Specification before shipment. The purity and concentration specification shown on this page is the manufacturer’s batch specification. Product-specific quality-control information travels with the order.
- Research-use discipline. Like every listing in our catalog, MGF is supplied for laboratory research use only, under strict research-use terms.
For buyers comparing chinese peptides suppliers, the practical test is whether the seller can name the manufacturer and show the batch documentation. We work the other way around: the manufacturer and the documentation are the offer. Browse the full catalog or see how sourcing works.
Available Variants
| Name | Strength | Pack Size | Purity | Availability |
|---|---|---|---|---|
| MGF | 2 mg | 10 vials | ≥98% | In Stock |
Specification Highlights
Quality & Testing
Testing method: HPLC / LC-MS ([“HPLC”,“LC-MS”,“Water Content”]) . Products are supplied against the specification shown on the applicable product page. The standard catalog purity specification is ≥98% unless otherwise stated. Product-specific specifications and quality-control information may vary by compound and batch. Available documentation: .
**Where provided, these documents reflect the manufacturer’s batch testing for this compound.
Research Areas
Satellite Cell Activation Research The primary research interest in MGF is its proposed role in activating skeletal muscle satellite cells (myosatellite cells) — quiescent stem cells that become activated following muscle damage or mechanical overload. Studies in rodent muscle injury models have examined satellite cell proliferation and myotube formation markers following MGF administration. The peptide’s local expression pattern (distinct from systemic IGF-1) and proposed non-IGF-1R mechanism make it a unique tool for studying satellite cell biology independently of canonical growth factor receptor pathways. Mechano-Transduction and Muscle Overload Models Research has examined MGF expression patterns in skeletal muscle following eccentric exercise, stretch overload, and myotoxin-induced injury in animal models. Studies tracking Ec peptide production relative to mechanical stimulus magnitude, timing, and recovery have contributed to understanding of how muscle senses and responds to mechanical challenge. MGF serves as a molecular marker of local IGF-1 Ec isoform upregulation in mechanobiology research. IGF-1 Isoform Pharmacology The IGF-1 gene produces multiple splice variants (IGF-1Ea, IGF-1Eb, IGF-1Ec in humans) with distinct tissue expression patterns and proposed functional roles. MGF (IGF-1Ec) research explores how the Ec C-terminal extension confers functional properties absent in the common Ea isoform — particularly local tissue action and satellite cell targeting. Comparative studies using Ea versus Ec peptide fragments in matched models are a key tool in IGF-1 isoform pharmacology.
Compound Profile
MGF (Mechano Growth Factor) is a splice variant of IGF-1 (Insulin-like Growth Factor 1), specifically the Ec isoform produced in response to mechanical load and tissue damage. Unlike systemic IGF-1 (which circulates from the liver and activates the IGF-1 receptor broadly), MGF is expressed locally in mechanically stressed or injured tissue — particularly skeletal muscle — where it is proposed to activate muscle satellite cells (myosatellite cells) and initiate repair and hypertrophy signaling. The research compound sold as MGF is typically the 24-amino acid C-terminal Ec peptide fragment, which is the domain of IGF-1Ec responsible for satellite cell activation. Preclinical research in rodent skeletal muscle injury and overload models has examined MGF’s role in satellite cell recruitment, proliferation, and differentiation. Proposed mechanisms involve a distinct receptor system from the canonical IGF-1R, operating via a non-IGF-1 receptor pathway — specifically hypothesized to involve CXCR4 or integrin-mediated signaling, though the precise receptor remains under investigation. MGF is also available as a PEGylated form (PEG-MGF) with extended half-life, providing a tool for comparing acute versus sustained Ec peptide signaling in research models. Peptides of China supplies MGF as a lyophilized powder at 99%+ purity, verified by HPLC and Mass Spectrometry. Every batch is tested by the manufacturer for purity and concentration as part of routine quality control. Both native MGF and PEG-MGF are available. All products are for laboratory research use only and are not for human consumption.
Profile
Research Areas
Skeletal muscle biology, satellite cell activation, mechanotransduction, IGF-1 isoform pharmacology, tissue repair
Available Variants
| Name | Strength | Pack Size | Purity | Availability |
|---|---|---|---|---|
| MGF | 2 mg | 10 vials | ≥98% | In Stock |
Specification Highlights
Quality & Testing
Testing method: HPLC / LC-MS ([“HPLC”,“LC-MS”,“Water Content”]) . Products are supplied against the specification shown on the applicable product page. The standard catalog purity specification is ≥98% unless otherwise stated. Product-specific specifications and quality-control information may vary by compound and batch. Available documentation: .
**Where provided, these documents reflect the manufacturer’s batch testing for this compound.
Research Areas
Satellite Cell Activation Research The primary research interest in MGF is its proposed role in activating skeletal muscle satellite cells (myosatellite cells) — quiescent stem cells that become activated following muscle damage or mechanical overload. Studies in rodent muscle injury models have examined satellite cell proliferation and myotube formation markers following MGF administration. The peptide’s local expression pattern (distinct from systemic IGF-1) and proposed non-IGF-1R mechanism make it a unique tool for studying satellite cell biology independently of canonical growth factor receptor pathways. Mechano-Transduction and Muscle Overload Models Research has examined MGF expression patterns in skeletal muscle following eccentric exercise, stretch overload, and myotoxin-induced injury in animal models. Studies tracking Ec peptide production relative to mechanical stimulus magnitude, timing, and recovery have contributed to understanding of how muscle senses and responds to mechanical challenge. MGF serves as a molecular marker of local IGF-1 Ec isoform upregulation in mechanobiology research. IGF-1 Isoform Pharmacology The IGF-1 gene produces multiple splice variants (IGF-1Ea, IGF-1Eb, IGF-1Ec in humans) with distinct tissue expression patterns and proposed functional roles. MGF (IGF-1Ec) research explores how the Ec C-terminal extension confers functional properties absent in the common Ea isoform — particularly local tissue action and satellite cell targeting. Comparative studies using Ea versus Ec peptide fragments in matched models are a key tool in IGF-1 isoform pharmacology.